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protein S100-P; S100 Ca+2-binding protein P (S100P S100E)

Function: - interacts with S100PBP & S100Z - binds 2 Ca+2 Structure: - homodimer - belongs to the S-100 family - contains 2 EF-hand domains Compartment: - nucleus, cytoplasm - colocalizes with S100PBP in the nucleus Pathology: - up-regulated in various pancreatic ductal adenocarcinomas & pancreatic intraepithelial neoplasias

Related

S100 Ca+2-binding protein

General

placental protein protein subunit

Properties

SIZE: entity length = 95 aa MW = 10 kD COMPARTMENT: cytoplasm cell nucleus MOTIF: EF hand SITE: 12-47 MOTIF: Ca+2-binding site SITE: 19-32 EF hand SITE: 49-84 MOTIF: Ca+2-binding site SITE: 62-73

Database Correlations

OMIM 600614 UniProt P25815 Pfam PF01023 Entrez Gene 6286 Kegg hsa:6286

References

  1. UniProt :accession P25815
  2. Atlas of Genetics & Cytogenetics in Oncology & Haematology http://atlasgeneticsoncology.org/genes/S100PID42196ch4p16.html
  3. Entrez Gene :accession 6286