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small G protein signaling modulator 2; RUN & TBC1 domain-containing protein 1 (SGSM2, RUTBC1, KIAA0397)
Function:
- interacts with RAB4A, RAB11A, RAP1A, RAP1B, RAP2A & RAP2B
- no interaction with RAB27A
Structure:
- belongs to the RUTBC family
- contains 1 Rab-GAP TBC domain
- contains 1 RUN domain
Alternative splicing: named isoforms=5
Expression: widely expressed
General
rab GTPase-activating protein (rab-GAP)
Properties
SIZE: MW = 113 kD
entity length = 1006 aa
MOTIF: RUN {34-191}
rab-GAP domain
NAME: rab-GAP domain
SITE: 566-939
Database Correlations
OMIM 611418
UniProt O43147
PFAM correlations
Entrez Gene 9905
Kegg hsa:9905
References
UniProt :accession O43147