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ribonucleoprotein [RNP] motif (RNA recognition motif, RRM)
A 90 amino acid segment containing 2 highly conserved segments RNP1 (RNP octomer consensus) & RNP2 motifs, considered to be an RNA-binding module.
Related
ribonucleic acid (RNA)
Specific
ribonucleoprotein-1 motif (RNP-1 motif, RNP-CS motif, ribonucleoprotein octomer consensus)
ribonucleoprotein-2 motif
General
RNA-binding motif
domain
Properties
NAME: RNP motif
FOR-BINDING-OF: ribonucleic acid
MOTIF: ribonucleoprotein-1 motif
ribonucleoprotein-2 motif
References
- Zamore PD, Zapp ML, Green MR.
Gene expression. RNA binding: beta s and basics.
Nature. 1990 Dec 6;348(6301):485-6. No abstract available.
PMID: 1701031
- Nagai K, Oubridge C, Jessen TH, Li J, Evans PR.
Crystal structure of the RNA-binding domain of the U1 small
nuclear ribonucleoprotein A.
Nature. 1990 Dec 6;348(6301):515-20.
PMID: 2147232
Components
ribonucleoprotein-1 motif (RNP-1 motif, RNP-CS motif, ribonucleoprotein octomer consensus)
ribonucleoprotein-2 motif