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romidepsin (Istodax)

Indications: - cutaneous T-cell lymphoma - stage 3 or 4 mycoses fungoides [2] Mechanism of action: - histone deacetylase inhibitor

General

histone decetylase inhibitor antineoplastic enzyme inhibitor

References

  1. Prescriber's Letter 17(2): 2010 New Drugs Approved by the FDA in 2009 Detail-Document#: 260213 (subscription needed) http://www.prescribersletter.com
  2. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015