Search
risk factors for cancer
Etiology:
risk factors
- noncancer health markers & disease are associated with excess risk for new cancer & cancer-related death [2]
- serum cholesterol < 240 mg/dL, inverse relationship > 240 mg/dL
- heart rate > 90/min
- diabetes mellitus & prediabetes
- proteinuria
- GFR < 60 or > 90 mL/min/1.73 m2
- uric acid < 300 umol/L
- physical activity mitigates these risks
- adverse life style [2]
- nonideal body-mass index
- alcohol consumption
- insufficient fruit & vegetable intake
- insufficient physical activity
- smoking
Management:
- see prevention of cancer
- moderate to vigorous physical activity associated with
- relative reduction in risk for 13 cancers
- 42% lower risk for esophageal adenocarcinoma
- 23% lower for renal carcinoma
- 20% lower for myeloid leukemia
- relative increase in risk for 2 cancers
- 27% higher risk for malignant melanoma
- 65% higher risk for prostate cancer
Related
malignant neoplasm (cancer)
prevention of cancer
screening for cancer
Specific
risk factors for breast cancer & management of high-risk women
risk factors for colon cancer in patients with ulcerative colitis
General
health risk factor(s)
References
- Moore SC et al.
Association of leisure-time physical activity with risk of 26
types of cancer in 1.44 million adults.
JAMA Intern Med 2016 May 16;
PMID: 27183032
- Tu H, Wen CP, Tsai SP, et al.
Cancer risk associated with chronic diseases and disease
markers: Prospective cohort study.
BMJ 2018 Jan 31; 360:k134
PMID: 29386192 Free PMC Article
http://www.bmj.com/content/360/bmj.k134