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retinoic acid syndrome

Etiology: - systemic chemotherapy with all-trans retinoic acid Clinical manifestations: - pulmonary infiltrates - hypoxemia Laboratory: - complete blood count (CBC) - leukocytosis (may occur) - arterial blood gas vs pulse oxymetry: hypoxemia Management: - dexamethasone

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retinoic acid

General

syndrome

References

Medical Knowledge Self Assessment Program (MKSAP) 14, American College of Physicians, Philadelphia 2006