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response to hypoxia (GO:0001666)
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 20.95%, results in metabolic adaptation at both the cellular and organismal level.
Notes:
- Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
Specific
cellular response to hypoxia (GO:0071456)
detection of hypoxia (GO:0070483)
General
response to decreased oxygen levels (GO:0036293)
response to stress (GO:0006950)
References
gene ontology: GO:0001666