Contents

Search

regulatory T cell

subsets of CD4+ cells Foxp3, GITR, LAG-3, CTLA4, CD25+, CD46+ CD4+ , Function: - suppress or regulate T-cells - T-regulatory 1 cells suppress immune responses by secreting IL-10, & thereby prevent autoimmunity (putative) - a number of viral & bacterial pathogens seem to exploit this property & directly induce an immunosuppressive phenotype in T-cells by binding to CD46

General

T lymphocyte (T-cell, thymocyte)

References

  1. Finn, PW UC San Diego
  2. UniProt :accession P15529
  3. Regulatory T-Cell Panel, FOXP3 Laboratory Test Directory ARUP: 3002249