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Brill-Zinsser disease (recrudescent typhus)
Etiology:
- endogenous reinfection with Rickettsia prowazekii associated with a carrier state in persons previously with epidemic typhus (recrudescent typhus)
Clinical manifestations:
- may occur 30-50 years after the original infection
Notes:
- 1st described by Brill in New York City, but not recognized as a recrudescent form of epidemic typhus until the work of Zinsser
Related
Rickettsia prowazekii
General
epidemic typhus
References
- Harrison's Principles of Internal Medicine, 14th ed.
Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 91
- Stedman's Medical Dictionary 27th ed, Williams &
Wilkins, Baltimore, 1999