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recombinant antithrombin (ATryn)

Indications: - hereditary antithrombin deficiency - *prevention of peri-operative & peri-partum thromboembolism - *treatment of established DVT Contraindications: - not indicated for treatment of thromboembolic events in the absence of hereditary antithrombin deficiency Mechanism of action: - recombinant antithrombin

Interactions

drug adverse effects of antithrombotic agent(s)

Specific

recombinant antithrombin-III

General

recombinant protein; chimer antithrombin

References

  1. Prescriber's Letter 17(2): 2010 New Drugs Approved by the FDA in 2009 Detail-Document#: 260213 (subscription needed) http://www.prescribersletter.com
  2. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015