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E3 ubiquitin-protein ligase TRIM17; tripartite motif-containing protein 17; testis RING finger protein; RING finger protein 16 (TRIM17, RBCC, RNF16, TERF)
Function:
- may function as an ubiquitin E3 ligase
- protein modification; protein ubiquitination
- auto-ubiquitinated
- interacts (via coiled coil) with TRIM44 (via coiled coil)
Structure:
- belongs to the TRIM/RBCC family
- contains 1 B box-type Zn+2 finger
- contains 1 B30.2/SPRY domain
- contains 1 RING-type Zn+2 finger
Expression: almost exclusively in the testis
General
tripartite motif-containing protein (trim protein)
E3 ubiquitin ligase; ubiquitin-ligating enzyme E3; N end-recognizing protein
Properties
SIZE: entity length = 477 aa
MW = 54 kD
MOTIF: RING-finger {16-66}
EFFECTOR-BOUND: Zn+2
FOR-BINDING-OF: DNA motif
zinc finger B box
SITE: 94-135
EFFECTOR-BOUND: Zn+2
coiled coil {135-223}
B30.2/SPRY {277-475}
Database Correlations
OMIM 606123
UniProt Q9Y577
PFAM correlations
Entrez Gene 51127
Kegg hsa:51127
References
UniProt :accession Q9Y577