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ras subfamily protein
Interactions
molecular events
Specific
GTP-binding protein RAY-like; Rab-like protein 4 (RABL4, RAYL, IFT27)
GTP-binding protein Rit1 (Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1, RIT1, RIBB, RIT, ROC1)
GTP-binding protein Rit2 (Ras-like protein expressed in neurons, Ras-like without CAAX protein 2, RIT2, RIN, ROC2)
GTPase ERas (E-Ras, embryonic stem cell-expressed Ras, v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2, ERAS, HRAS2, HRASP)
NF-kappa-B inhibitor-interacting Ras-like protein 1; I-kappa-B-interacting Ras-like protein 1; Kappa B-Ras protein 1; KappaB-Ras1 (NKIRAS1, KBRAS1)
NF-kappa-B inhibitor-interacting Ras-like protein 2; I-kappa-B-interacting Ras-like protein 2; Kappa B-Ras protein 2; KappaB-Ras2 (NKIRAS2 KBRAS2)
p21 v-ras oncoprotein
R-ras proto-oncogene protein (p21 R-ras)
ral proto-oncogene protein
ras proto-oncogene protein (p21ras)
ras-associated protein (rap)
Ras-like protein family 10 member B (Ras-like protein VTS58635, RASL10B)
Ras-like protein family member 11A (RASL11A)
Ras-like protein family member 11B (RASL11B)
Ras-like protein family member 12 (RAS-like protein Ris, RASL12 RIS)
Ras-like protein RRP22 (RASL10A)
Ras-related protein M-Ras; Ras-related protein R-Ras3 (MRAS, RRAS3)
Ras-related protein R-Ras2; Ras-like protein TC21; teratocarcinoma oncogene (RRAS2, TC21)
Ras1 protein
Ras2 protein
Rho-related GTP-binding protein RhoQ; Ras-related GTP-binding protein TC10; Ras-like protein family member 7A (RHOQ, ARHQ, RASL7A, TC10)
General
prenyl protein
proto oncogene protein
ras superfamily protein
Properties
SIZE: MW = 21 kD
COMPARTMENT: plasma membrane
CELL: unspecified cell type
ORGANISM: mammal
MOTIF: binding site
FOR-BINDING-OF: protein kinase
binding site
FOR-BINDING-OF: ras GTPase activator protein
P-loop
FOR-BINDING-OF: guanosine triphosphate
guanosine diphosphate
CaaX motif
SITE: C-TERMINUS
QUALITIES: AAX-TRUNCATED
CARBOXYMETHYLATED
EFFECTOR-BOUND: farnesyl
BOUND-VIA: cysteine residue
References
- Kahn RA, Der CJ, Bokoch GM.
The ras superfamily of GTP-binding proteins: guidelines on
nomenclature.
FASEB J. 1992 May;6(8):2512-3.
PMID: 1592203
- Wittinghofer A, Pai EF.
The structure of Ras protein: a model for a universal molecular
switch.
Trends Biochem Sci. 1991 Oct;16(10):382-7. Review.
PMID: 1785141
- Moodie SA, Willumsen BM, Weber MJ, Wolfman A.
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein
kinase kinase.
Science. 1993 Jun 11;260(5114):1658-61.
PMID: 8503013