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XP G-correcting protein gene, ERCC-5 or RAD2

Mutant gene in subset of Xeroderma Pigmentosum (XP G). Human homolog of rodent ERCC5 & yeast RAD2.

Related

DNA repair protein complementing XP-G cells; xeroderma pigmentosum group G-complementing protein; DNA excision repair protein ERCC-5 (ERCC5, ERCM2, XPG, XPGC)

General

unclassified gene

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: DNA repair protein complementing XP-G cells MOTIF: transcription factor binding site transcriptional start site exon intron transcriptional termination site

Database Correlations

OMIM 133530 MORBIDMAP 133530

References

- Bootsma D & Hoeijmakers JH DNA repair. Engagement with transcription. Nature 363:114 1993 PMID: 8483493