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quinapril (Accupril)

Tradename: Accupril. Dosage: 1) HTN. Start 10 mg PO QD, max 80 mg/day. 2) CHF: Start 5 mg PO BID, max 20 mg BID Tabs: 5, 10, 20, 40 mg. Adverse effects: - see ACE inhibitor * N-Nitroso-quinapril impurity found in 20 mg & Mechanism of action: - see ACE inhibitor

Interactions

drug interactions drug adverse effects (more general classes) monitor with ACE inhibitors

General

angiotensin-converting enzyme (ACE) inhibitor

Properties

INHIBITS: angiotensin converting enzyme MISC-INFO: elimination route LIVER KIDNEY pregnancy-category D safety in lactation ?

Database Correlations

PUBCHEM correlations

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. U.S. Food & Drug Administration. Dec 21, 2022 Lupin Pharmaceuticals, Inc. Issues Voluntary Nationwide Recall of Four Lots of Quinapril Tablets Due to Potential Presence of N-Nitroso-Quinapril Impurity. https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/lupin-pharmaceuticals-inc-issues-voluntary-nationwide-recall-four-lots-quinapril-tablets-due

Component-of

hydrochlorothiazide/quinapril