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quinacrine; mepacrine (Atrabine)
Tradename: Atrabine.
Indications:
1) Malaria suppression
2) subactue cutaneous lupus erythematosus (adjunct to hydroxychloroquine)
Dosage:
- 100 mg PO QD.
- pediatrics: 50 mg QD.
Tabs: 100 mg.
Adverse effects:
- bizarre yellow skin color, somewhat modified by beta-carotene 60 mg TID
Interactions
drug interactions
drug adverse effects of antimalarials
General
aminoacridine
antimalarial
Properties
MISC-INFO: elimination route LIVER
KIDNEY
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Color Atlas and Synopsis of Clinical Dermatology, Common
and Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY,
1997, pg 351.