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quadriplegia
Paralysis of all 4 extremities (i.e. both arms & legs) to a similar degree.
Clinical trials:
- brain-computer interface research offers promise [3]
- BrainGate2 clinical trial,
- two intracortical brain-computer interface (BCI) chips the size of a baby aspirin place into part of motor cortex that governs hand movement
- as patient imagined writing, a machine-learning algorithm used signals from individual neurons to recognize patterns produced with each letter
- this allowed patient to communicate in real time with text at a rate of 90 characters per minute [4]
Related
diplegia
monoplegia
paraplegia
General
paralysis
References
- Stedman's Medical Dictionary 26th ed, Williams &
Wilkins, Baltimore, 1995
- The Merck Manual, 14th ed, Merck, Sharp & Dohme, Rathway, NJ, 1982
- Hochberg LR et al,
Neuronal ensemble control of prosthetic devices by a human
with tetraplegia.
Nature 2006, 442:164
PMID: 16838014
- George J
Implanted Sensor Translates Brain Signals Into Text.
Brain-computer interface decodes handwriting movements from neural activity.
MedPage Today May 12, 2021
https://www.medpagetoday.com/neurology/generalneurology/92545
- Willet FR, Avansino DT, Hockberg LR et al
High-performance brain-to-text communication via handwriting.
Nature 2021 593(7858):249-254. May 12
PMID: 33981047
https://www.nature.com/articles/s41586-021-03506-2
- Rajeswaran P, Orsborn AL
Neural interface translates thoughts into type.
Nature 2021. 593(7858):197-198. May 12
PMID: 33981045
https://www.nature.com/articles/d41586-021-00776-8
- BrainGate2: Feasibility Study of an Intracortical Neural Interface System
for Persons With Tetraplegia (BrainGate2).
ClinicalTrials.gov
https://www.clinicaltrials.gov/ct2/show/NCT00912041