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NACHT, LRR & PYD domains-containing protein 9 (nucleotide-binding oligomerization domain protein 6, PYRIN & NACHT-containing protein 12, NLRP9, NALP9, NOD6, PAN12)
Function: role in inflammation (putative)
Structure:
- belongs to the NLRP family
- contains 1 DAPIN domain
- contains 3 LRR repeats (leucine-rich repeats)
- contains 1 NACHT domain
Compartment: cytoplasm
Alternative splicing: named isoforms=2
General
NACHT, LRR & PYD-containing protein (NALP)
Properties
SIZE: MW = 113 kD
entity length = 991 aa
COMPARTMENT: cytoplasm
MOTIF: DAPIN domain {1-94}
NACHT domain
NAME: NACHT domain
SITE: 146-465
MOTIF: ATP-binding site
NAME: ATP-binding site
SITE: 152-159
leucine-rich repeat
SITE: 741-768
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 798-821
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 855-878
MOTIF: leucine residue (SEVERAL)
Database Correlations
UniProt Q7RTR0
PFAM correlations
References
UniProt :accession Q7RTR0