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pyrantel (Antiminth)
Tradename: Antiminth. (pyrantel pamoate)
Indications:
- intestinal nematodes (helminth infection)
- Ancylostoma duodenale
- uncinariasis
- Necator americanus
- Ascaris lumbricoides
- Enterobius vermicularis
- Trichostrongyloidiasis
- moniliformis [4]
Contraindications:
- avoid during pregnancy
Dosage:
- pinworms & roundworms: 11 mg/kg up to 1 g PO single dose
Suspension: 50 mg/mL.
Mechanism of action:
- acts by inducing neuromuscular paralysis in the nematode which allows the host to expell them
Interactions
drug interactions
General
antihelmintic
Properties
MISC-INFO: elimination route FECES
pregnancy-category -
safety in lactation ?
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996.
- Harrison's Principles of Internal Medicine, 14th ed.
Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 1175
- Prescriber's Letter 19(3): 2012
Alternatives to Vermox for Treatment of Intestinal Worms
Detail-Document#: 280308
(subscription needed) http://www.prescribersletter.com
- Deprecated Reference
Component-of
febantel/praziquantel/pyrantel
ivermectin/praziquantel/pyrantel
ivermectin/pyrantel
moxidectin/pyrantel/sarolaner
praziquantel/pyrantel