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psychiatric disease; behavioral disorder

Clinical manifestations: - psychiatric disease manifests itself through behavioral disturbances Laboratory: - higher leukocyte count associated with increased risk* - higher serum C-reactive protein associated with increased risk* - higher serum haptoglobin associated with increased risk* - higher IgG associated with lower risk* * laboratory associatios with risk of psychiatric disease complications: - persons with one psychiatric disorder are more likely to have another [6] - decreased life expectancy (all psychiatric diseases) - 13.5-15.9 years in men - 10.4-12.0 years in women - decrease greatest for alcoholism & drug abuse - chronic disease (cardiovascular disease, cancer ...) account for 75% of decrease - suicide accounts for 14% of the decrease [1] management: - exercise via cybercycling integrated into physical education improves classroom functioning among children with behavioral disorders attending a therapeutic day school [4] - use of calcium-channel blockers, & metformin each associated with lower risk for psychiatric hospitalizations among all mental illness subgroups [5]* - self-harm risk lower with calcium-channel blocker use in all mental illness subgroups, & with statin & metformin use in patients with bipolar disorder & schizophrenia [5]* * adjusted hazzard ratios statistically significant, but modest & of unclear clinical significance (swedish study)

Related

brief psychiatric rating scale medications for mental health psychosis, agitation & difficult behavior in the elderly

Specific

addiction (psychological dependence) cataplexy conduct disorder critical illness neuropsychiatric impairment (post-ICU neuropsychiatric impairment) delusional disorder dissociative disorder factitious disorder feigning of symptoms hoarding impulse control disorder Morgellons disease neurosis paraphilia paraphrenia pathologic lying pediatric acute-onset neuropsychiatric syndrome (PANS) personality disorder psychogenic movement disorder; psychomotor disorder psychological trauma psychosis schizophrenia somatoform (psychosomatic) disorder; somatic symptom & related disorders (SSRD) stereotypy/habit disorder suicide suicide attempt

General

mental disorder

References

  1. Lawrence D et al. The gap in life expectancy from preventable physical illness in psychiatric patients in western australia: retrospective analysis of population based registers. BMJ 2013 May 21; 346:f2539. PMID: 23694688
  2. Huhn M et al. Efficacy of pharmacotherapy and psychotherapy for adult psychiatric disorders: a systematic overview of meta-analyses. JAMA Psychiatry 2014 apr 30 PMID: 24789675 http://archpsyc.jamanetwork.com/article.aspx?articleid=1865002 - Correll CU, Carbon M. Efficacy of pharmacologic and psychotherapeutic interventions in psychiatry: to talk or to prescribe: is that the question? JAMA Psychiatry 2014 apr 30 PMID: 24789579 http://archpsyc.jamanetwork.com/article.aspx?articleid=1865001
  3. Montross C Hard time or hospital treatment? Mental illness and the criminal justice system. N Engl J Med 2016; 375:1407-1409. october 13, 2016 http://www.nejm.org/doi/full/10.1056/nejmp1606083
  4. Bowling A, slavet j, miller dp et al Cybercycling effects on classroom behavior in children with behavioral health disorders: an rct. pediatrics. january 2017 PMID: 28069663 http://pediatrics.aappublications.org/content/early/2017/01/05/peds.2016-1985
  5. Jayes JF, lundin a, wicks s et al Association of hydroxylmethyl glutaryl coenzyme a reductase inhibitors, l-type calcium channel antagonists, and biguanides with rates of psychiatric hospitalization and self-harm in individuals with serious mental illness. JAMA Psychiatry published online january 9, 2019. PMID: 30624557 https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2719703
  6. Plana-Ripoll O, Pedersen CB, Holtz Y et al. Exploring comorbidity within mental disorders among a danish national population. JAMA Psychiatry 2019 jan 16; PMID: 30649197 - Hyman SE. New evidence for shared risk architecture of mental disorders. JAMA Psychiatry2019 jan 16 pmid: 30649144
  7. Zeng Y, Chourpiliadis C, Hammar N et al Inflammatory biomarkers and risk of psychiatric disorders. JAMA Psychiatry. 2024 aug 21:e242185. pmid: 39167384 https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2822344