MSS1 protein; 26S proteasome subunit 7 (PSMC2, MSS1)

Function: - regulatory ATPase of the 26S proteasome - confers ATP dependency & substrate specificity to the 26S proteasome - interacts with NDC80 & SQSTM1 - interacts with HIV-1 Tat, positive modulator of Tat-mediated transactivation Structure: belongs to the AAA ATPase family Compartment: cytoplasm, nucleus

Properties

SIZE: entity length = 433 aa MW = 49 kD COMPARTMENT: cytoplasm cell nucleus MOTIF: active site MOTIF: adenine nucleotide-binding site ATP-binding site NAME: ATP-binding site SITE: 216-223

Database Correlations

OMIM 154365 UniProt P35998 Pfam PF00004 Kegg hsa:5701

References

UniProt :accession P35998