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pseudoangiomatous stromal hyperplasia (PASH)

Epidemiology: - rare [1], not rare [2] - women age 18-86 years, mostly premenopausal & perimenopausal Pathology: - benign mesenchymal proliferative lesion of the breast Radiology: - no distinguishing feature(s) Management: - PASH without symptoms should not be routinely excised [5] - conservative surgery for larger (prsumptively symptomatic) masses [1]

General

breast disease; mammary gland disease hyperplasia

References

  1. Bowman E, Oprea G, Okoli J et al Pseudoangiomatous stromal hyperplasia (PASH) of the breast: a series of 24 patients. Breast J. 2012 May-Jun;18(3):242-7. PMID: 22583194 Free PMC Article
  2. AbdullGaffar B. Pseudoangiomatous stromal hyperplasia of the breast. Arch Pathol Lab Med. 2009 Aug;133(8):1335-8. Review. PMID: 19653734
  3. Genetic and Rare Diseases Information Center (GARD) Pseudoangiomatous stromal hyperplasia https://rarediseases.info.nih.gov/diseases/9410/pseudoangiomatous-stromal-hyperplasia
  4. Wikipedia: Pseudoangiomatous stromal hyperplasia https://en.wikipedia.org/wiki/Pseudoangiomatous_stromal_hyperplasia
  5. American Society of Breast Surgeons Benign Breast Disease. Five Things Physicians and Patients Should Question. Jan 8, 2018. http://www.choosingwisely.org/societies/american-society-of-breast-surgeons-benign-breast-disease/