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proton therapy
Indications:
- *treatment of cancers susceptible to radiation therapy
- bladder cancer
- breast cancer
- CNS neoplasm
- brain neoplasms
- gastrointestinal cancer
- colorectal cancer
- head & neck cancer [6]
- lung cancer
- proton therapy as effective as conventional radiotherapy but no less toxic [2,4]
- early NSCLC located too close to vital organs for conventional treatment may be amenable to proton beam therapy [3]
- lymphoma
- prostate cancer
- sarcomas
- testicular cancer
Specific
Flash radiotherapy
General
radiation therapy (XRT)
References
- SCripps
Proton Therapy for Cancer Treatment
http://campaigns.scripps.org/services/cancer-care__proton-therapy/conditions-treated
- Mulcahy N
Finally, RCT Results for Proton Therapy in a Cancer.
Medscape. Jun 21, 2016.
http://www.medscape.com/viewarticle/865137
- Susman E
Meeting Coverage.
RSNA: Protons Destroy Centrally Located Lung Cancer -
Early NSCLC close to vital organs found amenable to proton beam
approach.
MedPage Today. December 03, 2016
http://www.medpagetoday.com/MeetingCoverage/RSNA/61833
- Liao Z, Lee JJ, Komaki R et al
Bayesian Adaptive Randomization Trial of Passive Scattering
Proton Therapy and Intensity-Modulated Photon Radiotherapy
for Locally Advanced Non-Small-Cell Lung Cancer.
J Clin Oncol. 2018 Jan 2:JCO2017740720. [Epub ahead of print]
PMID: 29293386
- Lawrence L
Study: Proton Beam as Effective, Less Toxic Than Standard RT.
- But limitations make findings less than definitive.
MedPage Today. Dec27, 2019
https://www.medpagetoday.com/radiology/therapeuticradiology/84115
- Baumann BC, Mitra N, Harton JG et al
Comparative Effectiveness of Proton vs Photon Therapy as Part of
Concurrent Chemoradiotherapy for Locally Advanced Cancer.
JAMA Oncol. Published online Dec 26, 2019
PMID: 31876914
https://jamanetwork.com/journals/jamaoncology/article-abstract/2757520
- Harrison P
Proton Beam and Gabapentin Improve Care in Head and Neck Cancer.
Medscape - Nov 06, 2020.
https://www.medscape.com/viewarticle/940489