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proteoglycan
Complex glycoconjugates containing a core protein with a variable number of covalently attached glycosaminoglycan chains (i.e. heparin sulfate, chondroitin sulfate). The glycosaminoglycans are attached to the core proteins through a xyloside linked to Ser of the core protein.
Cell surface receptors often associate with cell-surface proteoglycan, which serves to non-specifically bind proteins & present them for specific binding to the receptor.
Interactions
molecular events
Related
proteoglycan core protein
proteoglycan link protein; cartilage link protein
Specific
chondroitin sulfate proteoglycan
dermatan sulfate proteoglycan
heparan proteoglycan
heparan sulfate proteoglycan
interphotoreceptor matrix proteoglycan 2 (sialoprotein associated with cones & rods proteoglycan, Spacrcan, interphotoreceptor matrix proteoglycan of 200 kD, IPM 200) (IMPG2 IPM200)
keratan sulfate proteoglycan
lectican; hyalectan
General
glycoconjugate
macromolecular complex
polysaccharide (complex carbohydrate, glycan)
protein
References
- Stryer Biochemistry WH Freeman & Co, New York, 1988 pg 276
- prosite :accession PS00002
Components
hyaluronate; hyaluronic acid; hyaluronan
proteoglycan core protein
proteoglycan link protein; cartilage link protein