dehydrogenase/reductase SDR family member 2 (HEP27 protein, protein D, DHRS2)

Function: - may inhibit cell replication either by a) catalyzing oxidation of estrogen & androgen b) converting cortisone in cortisol Structure: - belongs to the short-chain dehydrogenases/reductases (SDR) family Compartment: nucleus

Properties

SIZE: MW = 27 kD entity length = 257 aa COMPARTMENT: cell nucleus MOTIF: cofactor-binding site [17-41] COFACTOR-BOUND: NAD binding site SITE: 149-149 FOR-BINDING-OF: Substrate tyrosine residue {Y162}

Database Correlations

UniProt Q13268 Pfam PF00106 ENZYME 1.1.-.-

References

UniProt :accession Q13268