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protein
Polypeptide derived from translation of mRNA. The human genome contains about 20,000-25,000 protein-coding genes. [1]
Function:
- proteins are 'building blocks of life'
- proteins may have a diversity of functions
- proteins may associate to form transient or stable molecular complexes
Structure:
- the sequence of amino acids in a protein is defined by its mRNA transcribed from its gene
- amino acid residues in a protein may be chemically altered in post-translational modification
Compartment:
- a protein may be associated with a specific cellular or extracellular compartment
Expression:
- a protein may be specifically expressed by particular cell types
Pharmacokinetics:
- a protein may be stable or turnover rapidly
Pathology:
- a protein play a role in disease processes via:
a) overexpression
b) underexpression
c) aberrant structure & function
Interactions
molecular events
Related
dietary protein
protein (total) in serum
protein in 24 hour urine
protein in cerebrospinal fluid (CSF)
protein structure
protein synthesis
serum protein electrophoresis (SPE)
Specific
adhesion protein
amyloid
anti-oncoprotein (tumor suppressor protein)
apoprotein
apoptotic protein
bacterial protein
blood protein
Ca+2 binding protein
carrier protein (transporter)
centrosomal protein
chemically-modified protein
contractile protein
cryoprotein
cytoskeletal protein
enzyme
evolutionary divergent protein
fetal protein
filamentous protein
flavoprotein
fusion protein
globulin
glycoprotein
guanine nucleotide regulatory protein (GNRP)
heat shock protein
human longevity protein
hypothetical protein
initiation factor
invertebrate-specific protein
lectin
lipoprotein
membrane protein
metalloprotein
mitochondrial protein
multisubunit protein
myristoylated protein
nuclear protein
nucleoprotein
oncoprotein
other protein
peptide precursor
peptide termination factor
phosphoprotein
plant protein
prenyl protein
proline-rich protein
protein family member
protein precursor
protein product of a chromosomal translocation
protein subunit
proteoglycan
proteolipid
proto oncogene protein
protozoan protein
receptor
recombinant protein; chimer
ribosomal protein
RNA-binding protein
secreted protein
selenoprotein
shortened longevity protein
translation elongation factor
viral protein
General
polypeptide
Properties
References
- International Human Genome Sequencing Consortium.
Finishing the euchromatic sequence of the human genome.
Nature. 2004 Oct 21;431(7011):931-45.
PMID: 15496913
- WikiPedia: Protein
http://en.wikipedia.org/wiki/Protein
Component-of
molecular complex