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protein

Polypeptide derived from translation of mRNA. The human genome contains about 20,000-25,000 protein-coding genes. [1] Function: - proteins are 'building blocks of life' - proteins may have a diversity of functions - proteins may associate to form transient or stable molecular complexes Structure: - the sequence of amino acids in a protein is defined by its mRNA transcribed from its gene - amino acid residues in a protein may be chemically altered in post-translational modification Compartment: - a protein may be associated with a specific cellular or extracellular compartment Expression: - a protein may be specifically expressed by particular cell types Pharmacokinetics: - a protein may be stable or turnover rapidly Pathology: - a protein play a role in disease processes via: a) overexpression b) underexpression c) aberrant structure & function

Interactions

molecular events

Related

dietary protein protein (total) in serum protein in 24 hour urine protein in cerebrospinal fluid (CSF) protein structure protein synthesis serum protein electrophoresis (SPE)

Specific

adhesion protein amyloid anti-oncoprotein (tumor suppressor protein) apoprotein apoptotic protein bacterial protein blood protein Ca+2 binding protein carrier protein (transporter) centrosomal protein chemically-modified protein contractile protein cryoprotein cytoskeletal protein enzyme evolutionary divergent protein fetal protein filamentous protein flavoprotein fusion protein globulin glycoprotein guanine nucleotide regulatory protein (GNRP) heat shock protein human longevity protein hypothetical protein initiation factor invertebrate-specific protein lectin lipoprotein membrane protein metalloprotein mitochondrial protein multisubunit protein myristoylated protein nuclear protein nucleoprotein oncoprotein other protein peptide precursor peptide termination factor phosphoprotein plant protein prenyl protein proline-rich protein protein family member protein precursor protein product of a chromosomal translocation protein subunit proteoglycan proteolipid proto oncogene protein protozoan protein receptor recombinant protein; chimer ribosomal protein RNA-binding protein secreted protein selenoprotein shortened longevity protein translation elongation factor viral protein

General

polypeptide

Properties


References

  1. International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature. 2004 Oct 21;431(7011):931-45. PMID: 15496913
  2. WikiPedia: Protein http://en.wikipedia.org/wiki/Protein

Component-of

molecular complex