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prostaglandin I3
Produced by cyclooxygenase-2 in vascular endothelium. PGI2 is a vasodilator & inhibits platelet aggregation.
Interactions
molecular events
Related
eicosapentaenoate cyclooxygenase cascade
General
5,8,11,14,17-eicosapentaenoic acid [C20:5w3]
prostaglandin I (prostacyclin, epoprostenol {Flolan})
Properties
SIZE: MW = 302.4 G/MOL
COMPARTMENT: membrane
References
- Lands FASEB J 6:2530 1992
- Journal Watch 22(10):78, 2002
Cheng Y et al, Science 296:539, 2002
Vane JR, Science 296:474, 2002