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prostaglandin I2

Produced by cyclooxygenase-2 in vascular endothelium. PGI2 is a vasodilator & inhibits platelet aggregation.

Interactions

molecular events

Related

arachidonate cyclooxygenase cascade

General

arachidonate; arachidonic acid [C20:4w6, ARA] prostaglandin I (prostacyclin, epoprostenol {Flolan})

Properties

SIZE: MW = 304.5 G/MOL COMPARTMENT: membrane

References

Journal Watch 22(10):78, 2002 Cheng Y et al, Science 296:539, 2002 Vane JR, Science 296:474, 2002