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properdin
Interactions
molecular events
Related
complement cascade
General
beta globulin
complement
protein precursor
Properties
COMPARTMENT: plasma
MOTIF: proteolytic site
TSP1 module (6)
PRECURSOR-FOR: properdin factor B
COMPARTMENT: extracellular compartment
MOTIF: proteolytic site
binding site (3)
FOR-BINDING-OF: complement C1 inhibitor
PRECURSOR-FOR: properdin factor Bb
MOTIF: charge relay system
MOTIF: aspartate residue
histidine residue
serine residue
allosteric site (3)
FOR-BINDING-OF: complement C1 inhibitor
properdin factor D
COMPARTMENT: extracellular compartment
MOTIF: active site
SECRETED-BY: adipocyte
Database Correlations
OMIM 312060
UniProt P27918
References
- Baron M, Norman DG, Campbell ID.
Protein modules.
Trends Biochem Sci. 1991 Jan;16(1):13-7. Review.
PMID: 2053133
Component-of
complement complex C3bBbP