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primary intracranial embryonal carcinoma
Microscopic pathology:
- cells of primitive epithelial appearance
- variable patterns - solid, poorly formed glands
- mitotically active
- focal necrosis
Immunopathology:
- cytokeratin +
- placental alkaline phosphatase +
- alpha-fetoprotein -
- human chorionic gonadotropin -
- human placental lactogen -
General
embryonal carcinoma
primary intracranial germ cell neoplasm
References
- WHO Classification Tumours of the Nervous System.
Kleihues & Cavenee eds. IARC Press 2000