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prenatal genetic testing
Notes:
- standard of care is testing via amniocentesis
- tests based on fetal DNA in mother's blood introduced [3]
- testing for aneuploidy: trisomy 13, trisomy 18 & trisomy 21
- testing for uniparental disomy
- testing for fetal sex [3]
- pregnant women educated about the potential risks & benefits of prenatal genetic screening are less likely to elect for screening [2]
General
DNA (genetic) testing
References
- Weaver C
Tough Calls on Prenatal Tests.
Companies Race to Promote New Genetic Screen for Down Syndrome;
Worries About Patient Confusion.
Wall Street Journal. April 3, 2-13
http://online.wsj.com/article/SB10001424127887324883604578398791568615644.html
- Kuppermann M et al
Effect of Enhanced Information, Values Clarification, and
Removal of Financial Barriers on Use of Prenatal Genetic
Testing. A Randomized Clinical Trial.
JAMA. 2014;312(12):1210-1217
PMID: 25247517
http://jama.jamanetwork.com/article.aspx?articleid=1906614
- Dolan SM
Personalized Genomic Medicine and Prenatal Genetic Testing.
JAMA. 2014;312(12):1203-1205.
PMID: 25247514
http://jama.jamanetwork.com/article.aspx?articleid=1906588
- Allyse MA, Wick MJ
Noninvasive Prenatal Genetic Screening Using Cell-free DNA.
JAMA. Published online July 30, 2018
PMID: 30073283
https://jamanetwork.com/journals/jama/fullarticle/2695950