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premature termination codon
The occurrence of a termination codon within mRNA in an upstream location rendering translation of a truncated protein. These premature termination codons are discriminated from true termination codons by downstream cis-elements, such as exon-exon junctions.
General
termination codon
References
- Lykke-Anderson J et al
Human Upf proteins target an mRNA for nonsense-mediated
decay when bound downstream of a termination codon.
Cell 103:1121-31, 2000
PMID: 11163187