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premature ejaculation

Persistent or recurrent ejaculation with minimal sexual stimulation before, upon, or shortly after penetration & before the person wishes it. Etiology: organic factors are rarely the cause Epidemiology: 1) most prevalent form of male sexual dysfunction 2) affects 30% of men Clinical manifestations: - generally present with onset of sexual activity Management: 1) behavioral strategies focusing on awareness - limited benefit 2) selective serotonin-reuptake inhibitors 1st line [1] - paroxetine may be most effective SSRI [1] 4) topical lidocaine 3) clomipramine of modest benefit

General

ejaculatory dysfunction

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 11, 18, 19. American College of Physicians, Philadelphia 1998, 2018, 2022.
  2. Liu H, Zhang M, Huang M, et al. Comparative efficacy and safety of drug treatment for premature ejaculation: a systemic review and Bayesian network meta-analysis. Andrologia. 2020;52:e13806. PMID: 32892379