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prekallikrein (Fletcher Factor) in plasma
Indications:
- workup of coagulation disorder
Clinical significance:
- routine prolonged PTT evaluation finds no explanation
- PTT is normal in the mixing study
- factor VIII, factor IX, factor XI, & factor XII are normal
- prothrombin time & plasma fibrinogen are normal
- lupus anticoagulant assays are negative
- if prekallikrein assays are normal, HMW kininogen assays may be considered
Related
prekallikrein
General
clinical coagulation test
References
- Coagulation Test Handbook: Prekallikrein
http://mghlabtest.partners.org/coagbook/CO002600.htm