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phosphatase-2A regulatory subunit B' beta (PP2A, B subunit, B' beta isoform; PP2A, B subunit, B56 beta isoform; PP2A, B subunit, PR61 beta isoform; PP2A, B subunit, R5 beta isoform; PPP2R5B)
Function:
- B regulatory subunit might modulate substrate selectivity & catalytic activity, & also might direct the localization of the catalytic enzyme to a particular subcellular compartment
Structure:
- belongs to the phosphatase 2A regulatory subunit B56 family
Compartment: cytoplasm
Alternative splicing: named isoforms=2
Expression:
- highest expression in brain
- induced by retinoic acid in neuroblastoma cell lines
Related
phosphatase-2A (ceramide-activated protein phosphatase)
General
phosphatase-2A B subunit
Properties
SIZE: entity length = 497 aa
MW = 57 kD
COMPARTMENT: cytoplasm
MOTIF: binding site
FOR-BINDING-OF: ceramide
Database Correlations
OMIM 601644
UniProt Q15173
Pfam PF01603
Kegg hsa:5526
References
UniProt :accession Q15173