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POU domain

(pronounced 'pow') A 70-75 amino-acid residue domain found upstream of a homeobox domain in some eukaryotic transcription factors. It is thought to confer high-affinity site-specific DNA-binding & to mediate cooperative protein-protein interaction on DNA.

Related

DNA motif POU protein

General

homeodomain

Properties

MISC-INFO: LENGTH 76 AMINO_ACID_RESIDUES

References

  1. Herr Nature 350:554 1991
  2. Li et al Nature 347:528 199
  3. prosite :accession PS00035