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podophyllotoxin; podofilox (Condylox)
Tradename: Condylox. 0.5% purified solution.
Indications:
- condylomata acuminata (anogenital warts)
Dosage:
1) apply topically BID for 3 consecutive days
2) withold use for 4 days
3) repeat cycle up to 4 times until there is no visible wart
Gel topical: 0.05% (3.5 g)
1) topical agent applied weekly at home.
2) apply to external warts twice daily for 3 days, then discontinue for 4 days. Continue for 6-8 weeks.
Adverse effects:
1) local erythema
2) local irritation (burning, itching, inflammation
3) local erosion
Interactions
drug interactions
Related
epipodophyllotoxin
General
antiviral agent
aromatic compound
Properties
MISC-INFO: pregnancy-category C
safety in lactation ?
Database Correlations
PUBCHEM correlations
References
- Saunders Manual of Medical Practice, Rakel (ed), WB Saunders,
Philadelphia, 1996, pg 959
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Kaiser Permanente Northern California Regional Drug
Formulary, 1998
- Department of Veterans Affairs, VA National Formulary