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pluripotential stem cell
Primordial stem cells derived from totipotential stem cells of the embryonic morula, first appear as embryonic stems cells of the blastocyst. Pluripotential stem cells can differentiate into cells of any of the 3 germ layers: endoderm, ectoderm, mesoderm. Mesenchymal stem cells are the most prominent pluripotent cell in developing embryos.
Pluripotential stem cells are inducible from differentiated cells (fibroblasts) [2] (see induced pluripotential stem cell)
A cylindrical structure seeded with pluripotential stem cells & exposed to growth factors produced small cylinders of intestinal epithelium & mesenchyme [5]
Also see stem cell
Specific
embryonic stem (ES) cell
induced pluripotent stem cell (iPS)
mesenchymal cell
mesenchymal stem cell
multipotent adult progenitor cell (MAPC)
pleuripotential hematopoietic stem cell
General
stem cell
References
- Stedman's Medical Dictionary 27th ed, Williams &
Wilkins, Baltimore, 1999
- Takahashi K et al,
Induction of pluripotent stem cells from adult human
fibroblasts by defined factors.
Cell 2007, Nov 20, 131:861
PMID: 18035408
http://dximages.cell.com/images/images/cell/ieps/3661.pdf
Yu J et al,
Induced pluripotent stem cells derived from human somatic
cells.
Science 2007, Nov 20
PMID: 18029452
http://dx.doi.org/10.1126/science.1151526
- Wikipedia: Stem cell
http://en.wikipedia.org/wiki/Stem_cell
- Samuel R et al.
Generation of functionally competent and durable engineered
blood vessels from human induced pluripotent stem cells.
Proc Natl Acad Sci U S A 2013 Jul 30
PMID: 23861493
http://www.pnas.org/content/110/31/12774
- Takebe T et al.
Vascularized and functional human liver from an iPSC-derived
organ bud transplant.
Nature 2013 Jul 25; 499:481
PMID: 23823721
- Watson CL et al.
An in vivo model of human small intestine using pluripotent
stem cells.
Nat Med 2014 Nov; 20:1310.
PMID: 25326803