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platelet antibody in serum

Indications: - thrombocytopenia - immune thrombocytopenic purpura (not useful) [5] Clinical significance: - may be associated with heparin-administration & heparin-induced thrombocytopenia - may be other cause of thrombocytopenia - specificity high 93%, but sensitivity low 53% for ITP [6]

Related

platelet

Specific

drug-associated platelet antibody in serum platelet IgA Ab in serum platelet IgG Ab in serum platelet IgM Ab in serum

General

platelet associated antibody

References

  1. Medline Plus: Platelet associated antibodies http://www.nlm.nih.gov/medlineplus/ency/article/003552.htm
  2. Platelet Antibodies, Indirect Laboratory Test Directory ARUP: 51050
  3. Platelet Antibodies, Indirect Laboratory Test Directory ARUP: 51718
  4. Platelet Associated Antibodies, Direct Assay Laboratory Test Directory ARUP: 95614
  5. Medical Knowledge Self Assessment Program (MKSAP) 17, 18 American College of Physicians, Philadelphia 2015, 2018
  6. Vrbensky JR, Moore JE, Arnold DM, Smith JW, Kelton JG, Nazy I. The sensitivity and specificity of platelet autoantibody testing in immune thrombocytopenia: a systematic review and meta-analysis of a diagnostic test. J Thromb Haemost. 2019 May;17(5):787-794 Epub 2019 Mar 20. PMID: 30801909 https://onlinelibrary.wiley.com/doi/abs/10.1111/jth.14419