Search
plasma cell leukemia
Etiology:
- primary disease
- leukemic phase of multiple myeloma [1]
Epidemiology:
- rare
Pathology:
- plasmacytomas
Clinical manifestations:
- multiple exophytic subcutaneous lesions involving the arms & legs [1] (image)
Laboratory:
- complete blood count
- anemia, thrombocytopenia, leukocytosis
- peripheral smear - 25% plasma cells (histopathology) [1]
Complications:
- sepsis with multiorgan failure [1]
Management:
- comfort care [1]
Interactions
disease interactions
Related
multiple myeloma; plasmacytoma/plasma cell myeloma
General
lymphoid leukemia
peripheral B-cell lymphoid neoplasm
plasma cell dyscrasia
References
- Khan U, Hadid T (image, histopathology)
Plasmacytomas and Plasma-Cell Leukemia.
N Engl J Med 2017; 376:e19. March 16, 2017
PMID: 28296609
http://www.nejm.org/doi/full/10.1056/NEJMicm1611205