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placental transfusion

Procedure: - delaying clamping of umbilical cord holding the infant for > 1 min at the level of the vagina - placing the infant on the mother's chest or abdomen is as effective as holding infant at the level of the vagina [3] Clinical significance: - delaying clamping of umbilical cord (3 minutes or more rather than 10 seconds after birth) allows placental transfusion which increases to total blood volume by almost 1.3; at 4 months of age delayed clamping increases serum ferritin (117 vs 81 ug/L) & lowers prevalence of iron deficiency (0.6% vs 5.7%); blood hemoglobin levels at 4 months are unchanged by delayed clamping [1] Complications: - need for phototherapy for hyperbilirubinemia is more common with placental transfusion

General

blood transfusion

References

  1. Andersson O et al Effect of delayed versus early umbilical cord clamping on neonatal outcomes and iron status at 4 months: a randomised controlled trial BMJ 2011;343:bmj.d7157 PMID: 22089242 http://www.bmj.com/content/343/bmj.d7157 - van Rheenen P Delayed cord clamping and improved infant outcomes BMJ 2011;343:bmj.d7127 PMID: 22089240 http://www.bmj.com/content/343/bmj.d7127
  2. McDonald SJ et al Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes. Cochrane Database Syst Rev. 2013 Jul 11;7:CD004074 PMID: 23843134 http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004074.pub3/abstract
  3. Vain NE et al Effect of gravity on volume of placental transfusion: a multicentre, randomised, non-inferiority trial. The Lancet, Early Online Publication, 17 April 2014 PMID: 24746755 http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2814%2960197-5/abstract