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chorionic somatomammotropin hormone; choriomammotropin; lactogen; placental lactogen; PL

Function: - produced only during pregnancy - involved in stimulating lactation, fetal growth & metabolism - does not interact with GHR - activates PRLR through Zn+2-induced dimerization Structure: - belongs to the somatotropin/prolactin family - CSH1 sequence only differs from CSH2 sequence in 1 amino acid residue Compartment: secreted Notes: - apparently 2 different choriomammotropins that differ by only - amino acid residue

Specific

chorionic somatomammotropin hormone 1; choriomammotropin-1 (CSH1) chorionic somatomammotropin hormone 2; choriomammotropin-2 (CSH2) chorionic somatomammotropin hormone-like 1; chorionic somatomammotropin-like; lactogen-like (CSHL1, CSHP1, CSL)

General

gonadotropin secreted peptide

Properties

COMPARTMENT: extracellular compartment

References

  1. UniProt :accession P0DML2
  2. UniProt :accession P0DML3