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pim-1 proto-oncogene

pim-1 may be constitutively transcribed & regulated by trans- criptional attenuation via premature transcriptional termination. Note: There is a pim1 gene in Saccharomyces pombe that is a homolog of RCC1. The product of the yeast gene is a serine/threonine kinase implicated in coupling S -> M phase transition in the cell cycle.

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pim1 proto-oncogene protein

General

primary-response gene or immediate-early gene proto-oncogene

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: pim1 proto-oncogene protein LOCUS: human chromosome-6 P21.3-12 SIZE: entity length = 6.1 KB MOTIF: CpG island transcription factor binding site transcriptional start site exon (5) exon MOTIF: trinucleotide repeat REPEAT: CAG intron (4) transcriptional termination site

Database Correlations

OMIM 164960

References

  1. OMIM :accession 164960
  2. Nagarajan & Narayana Biochem Biophys Res Comm 190:435 1993
  3. Reeves et al Gene 90:303 1990
  4. Mizuno et al. Biochemical & Biophysical Research Communications 281:663-669, 2001