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zinc finger protein PILOT; early growth response protein 3; EGR-3 (EGR3, PILOT)

Function: - probable transcription factor involved in muscle spindle development Structure: - belongs to the EGR C2H2-type Zn+2-finger protein family - contains 3 C2H2-type Zn+2 fingers Compartment: nucleus (probable) Expression: - in T-cells, expressed 20 minutes following activation

General

C2H2 type zinc finger protein early growth response protein family (EGR)

Properties

SIZE: MW = 43 kD entity length = 387 aa COMPARTMENT: cell nucleus MOTIF: Zn finger C2H2-type SITE: 275-299 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 305-327 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 333-355 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q06889 Pfam PF00096 Entrez Gene 1960 Kegg hsa:1960

References

  1. UniProt :accession Q06889
  2. Gashler A and Sukhatme VP Early growth response protein 1 (EGR-1): prototype of a zinc- finger family of transcription factors. Prog Nuclei Acid Res Mol Biol 1995, 50:191 PMID: 7754034
  3. Entrez Gene :accession 1960