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pili torti (twisted hairs)

Etiology: - Bjoernstad syndrome - Menke disease - ectodermal dysplasia - Bazex syndrome - acquired forms - oral retinoids - anorexia nervosa - malnutrition - cutaneous lupus erythematosus Clinical manifestations: - hair shafts are flattened at irregular intervals & twisted 180 degrees from the normal axis, making the hair extremely brittle - usually recognized early in childhood Management: - treat or stop offending etiology (if feasible) - satin pillowcase - avoid excessive grooming, braiding, heat treatments, dying & coloring of hair - reduce exposure to sunlight (wear a hat) - use gentle shampoos

General

hair disease

References

  1. UniProt :accession Q9Y276
  2. Wikipedia: Pili torti http://en.wikipedia.org/wiki/Pili_torti
  3. Pili torti Genetic and Rare Diseases Information Center (GARD) http://rarediseases.info.nih.gov/GARD/Condition/4361/QnA/29631/Pili_torti.aspx