phosphatidylinositol glycan anchor biosynthesis class U protein; cell division cycle protein 91-like 1; protein CDC91-like 1; GPI transamidase component PIG-U (PIGU, CDC91L1, PSEC0205, UNQ3055/PRO9875)

Function: - component of the GPI transamidase complex - may be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI - glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis - forms a complex with PIGK/GPI8, PIGS, PIGT & GPAA1/GAA1 Structure: belongs to the PIGU family Compartment: - endoplasmic reticulum membrane; multi-pass membrane protein (putative) Alternative splicing: named isoforms=2

General

glycoprotein transmembrane 9 protein

Properties

SIZE: entity length = 435 aa MW = 50 kD COMPARTMENT: endoplasmic reticulum MOTIF: transmembrane domain {66-86} transmembrane domain {166-186} transmembrane domain {188-208} transmembrane domain {237-257} transmembrane domain {259-279} May be involved in recognition of long- chain fatty acids in GPI {269-289} transmembrane domain {286-306} transmembrane domain {313-333} transmembrane domain {355-375} transmembrane domain {386-406}

Database Correlations

OMIM 608528 UniProt Q9H490 Pfam PF06728 Entrez Gene 128869 Kegg hsa:128869

References

UniProt :accession Q9H490