phosphatidylinositol-glycan biosynthesis class F protein; PIG-F; GPI11 homolog (PIGF)

Function: - role in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI - glycolipid biosynthesis; GPI-anchor biosynthesis - forms a complex with PIGG & PIGO - PIGF is required to stabilize PIGG & PIGO Structure: - belongs to the PIGF family Compartment: - endoplasmic reticulum membrane - multi-pass membrane protein (putative) Alternative splicing: named isoforms=2

General

phosphatidylinositol-glycan biosynthesis protein (PIG-protein) transmembrane 6 protein

Properties

SIZE: entity length = 219 aa MW = 25 kD COMPARTMENT: endoplasmic reticulum MOTIF: transmembrane domain {11-31} transmembrane domain {42-62} transmembrane domain {86-106} transmembrane domain {113-133} transmembrane domain {155-175} transmembrane domain {189-209}

Database Correlations

OMIM 600153 UniProt Q07326 Pfam PF06699 Entrez Gene 5281 Kegg hsa:5281

References

UniProt :accession Q07326