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Pickwickian syndrome
Epidemiology: 5% of cases of sleep apnea.
Pathology:
1) efficiency of respiratory muscles is 60-70% of normal
2) in later stages, right heart failure is followed by left heart failure
3) cor pulmonale
Clinical manifestations:
1) morbid obesity
2) hypersomnolence
3) cyanosis
4) plethora
5) obstructive sleep apnea
Laboratory:
1) complete blood count (CBC)
- polycythemia
2) arterial blood gas (ABG)
a) hypoxia
b) hypercarbia
General
obstructive sleep apnea (OSA)
syndrome
References
- Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed)
Lippincott-Raven, Philadelphia, 1998, pg 750
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998