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phosphorylated tau231 in serum/plasma
Clinical significance:
- plasma p-tau217 outperforms plasma p-tau181 & plasma p-tau231 & other plasma biomarkers of Alzheimer's disease in identifying which patients may benefit from an anti-beta-amyloid anti-Alzheimer monoclonal antibody [1]
General
phosphorylated tau in serum/plasma
References
- George J
Alzheimer's Blood Test Predicts Who Might Benefit Most From Anti-Amyloid Drugs.
Novel two-cutoff approach may reduce need for confirmatory PET scans.
MedPage Today December 5, 2023
https://www.medpagetoday.com/neurology/alzheimersdisease/107691
- Mattsson-Carlgren N, Collij LE, Stomrud E et al
Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for
Antiamyloid Immunotherapies.
JAMA Neurol. Published online December 4, 2023.
PMID: 38048096
https://jamanetwork.com/journals/jamaneurology/article-abstract/2812432