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phosphoribosyl pyrophosphate synthetase deficiency

Epidemiology: - rare Genetics: deficiency in PRPS1 associated with - Charcot-Marie-Tooth disease type 5 - ARTS syndrome - X-linked deafness 1

Related

phosphoribosyl pyrophosphate [PRPP] synthetase; ribosephosphate pyrophosphokinase

General

carbohydrate inborn error of metabolism

References

  1. Phosphoribosylpyrophosphate synthetase deficiency Genetic and Rare Diseases Information Center (GARD) http://rarediseases.info.nih.gov/GARD/Condition/4337/Phosphoribosylpyrophosphate_synthetase_deficiency.aspx
  2. OMIM :accession 311850