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phosphatidylserine synthase; serine-exchange enzyme 1; CDP diacylglycerol serine O-phosphatidyltransferase (PTDSS1)
Function:
- catalyzes a base-exchange reaction in which the polar head group of phosphatidylcholine is replaced by L-serine
- phosphatidylserine biosynthesis
- may provide a precursor for the biosynthesis of phosphatidylethanolamine
- phosphatidylserine can be decarboxylated to phosphatidylethanolamine
Structure: belongs to the phosphatidyl serine synthase family
Compartment: membrane
Related
phosphatidylserine synthase 2 (Ptdser synthase 2, PSS-2, serine-exchange enzyme 2, PTDSS2, PSS2)
General
membrane protein
phosphotransferase
Properties
SIZE: MW = 56 kD
entity length = 473 aa
COMPARTMENT: cellular membrane
MOTIF: transmembrane domain {36-56}
transmembrane domain {73-93}
transmembrane domain {103-123}
transmembrane domain {161-181}
transmembrane domain {187-207}
transmembrane domain {217-237}
transmembrane domain {287-307}
transmembrane domain {310-330}
transmembrane domain {356-376}
transmembrane domain {384-404}
Database Correlations
UniProt P48651
ENZYME 2.7.8.8
References
UniProt :accession P48651